Bidirectional association between handgrip strength and ADLs disability: a prospective cohort study

Background Decreased handgrip strength (HGS) and activities of daily living (ADL) disability are common in aging populations. No studies have evaluated the bidirectional associations between HGS ADL disability. This study aimed to explore effects Methods analyzed data from two waves (2011 2015) China Health Retirement Longitudinal Study (CHARLS). Low is defined by Asian Working Group for Sarcopenia criteria. Meanwhile, was assessed ADLs scale. The prospective association examined using binary logistic regression. Subgroup analysis were performed according age gender. Results A total 4,902 5,243 participants included Stage I II analyses, respectively. On one hand, low significantly associated with subsequent odds ratio (OR) value developing BADL IADL 1.60 (95% confidence interval (CI): 1.23–2.08) 1.40 CI: 1.15–1.70), respectively, HGS. other baseline an increased risk OR 1.84 1.34–2.51) 1.46 1.19–1.79) disability, Lastly, varied among subgroups. Conclusions significant identified Interventions should be developed prevent development or progression both